The MACS® match maker
Unlock new possibilities in your research today – because every target deserves its perfect match!
Experience a robust platform that delivers quantitative data on binder affinity, kinetics, and specificity.
This advanced biomolecular interaction system is not just another tool, it is designed to address your lab’s biggest challenges and redefine the way you approach drug discovery and interaction studies.
- Label-free measurements in crude media: in vivo-like environment and eliminate the hassle of pre-purification saving time.
- Simple assay development: Leverage our easy-to-use sensor functionalization protocol to set up your experiments faster than ever.
- Multiplexing for increased speed: Characterize 54 interactions simultaneously, significantly reducing experiment times.
- Assay automatization: Use the MACS® sampler for fully unattended runs in combination with up to 2 x 384 well plates.
- Drift-free data: Experience robust and more reliable data with minimized artifacts by our patented focal molography technology.
- pM Sensitivity: Characterize even small proteins or peptides in complex biological matrices.
- Data availability: Control of your data at all time from any place by our platform independent software solutions.
The MACS® match maker
Unlock new possibilities in your research today – because every target deserves its perfect match!
Our unique technology for in situ analysis of molecular interactions in complex biological samples
Focal molography is a biophysical technique that enables robust and sensitive detection of biomolecular interactions without the need for fluorescent labels. This method facilitates the analysis of these interactions within complex biological samples, such as blood sera, bioreactor fluids, or cell culture media.
The technique operates by diffracting laser light through a specialized two-dimensional nanopattern of molecular binding sites on a sensor chip, known as a mologram. This mologram functions as a focusing diffractive lens, directing light into a precise focal point. The intensity of this focused light correlates with the quantity of molecules bound to the mologram, thereby indicating the extent of biomolecular interactions.
A significant advantage of focal molography is its resilience against environmental noise, such as temperature fluctuations and nonspecific binding of off-target molecules. This robustness eliminates the need for temperature stabilization or sensor equilibration, making it a versatile tool for various applications.
Overall, focal molography expands the analytical capabilities for studying biomolecular interactions across a wide range of biological research and diagnostic applications.